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Estrogen therapy may change how your body handles other drugs

NCT ID NCT05469204

First seen Jan 11, 2026 · Last updated May 23, 2026 · Updated 13 times

Summary

This study looked at how gender-affirming estrogen therapy changes the way the body processes other medications. Twenty-two transgender adults who were not yet on estrogen took part. Researchers measured how two common drugs (midazolam and digoxin) were handled before and after starting estrogen. The goal was to understand potential drug interactions and improve safe prescribing.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Washington

    Seattle, Washington, 98195, United States

Conditions

Explore the condition pages connected to this study.