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Estrogen's secret Muscle-Boosting power revealed in new study

NCT ID NCT07617454

Knowledge-focused Sponsor: Mette Hansen Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether taking estrogen helps post-menopausal women gain more muscle from exercise. Thirty women who are 1-10 years past their last period will take either estrogen or a placebo and do 12 weeks of strength training. Researchers will measure muscle mass and function to understand how estrogen affects muscle health.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2026

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 years and older

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 1-10 years since last menstrual bleeding * Age \> 40 years old * BMI 20-30 Exclusion Criteria: * Follicular stimulating hormone \< 30 mmol/L * Systematic strength training during the last year (\> 1 strength training session per week) * Injuries to the legs which may prevent participation in the physical training program * Magnetizable metals or electrical devices implanted in the body, such as a pacemaker * Use of medication that can influence the effect of immobilization and/or training * Muscular or joint disorders which may affect the results * Metabolic diseases (such as diabetes and cardiovascular diseases) * Previous or present liver or cancer disease * Current or previous thrombosis * Porphyria * Epilepsia * Systemic autoimmune disease * Edema * Smoking or use of other nicotine containing products * Claustrophobia * Addictive behavior, defined as abuse of cannabis, opioids, or other intoxicating substances. * Lack of ability to cooperate * Blood parameters out of normal range at the health check * Blood pressure above 140/90 mmHg

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Conditions

The condition(s) this trial relates to.

Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Exercise training Menopause related conditions

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Aarhus University

    RECRUITING

    Aarhus, Jutland, 8000, Denmark

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