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Timing of nerve block may cut opioid use in back surgery

NCT ID NCT06933498

Symptom relief Sponsor: Ankara Ataturk Sanatorium Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at whether giving a nerve block (ESPB) before or during lumbar disc surgery better reduces pain and the need for strong painkillers. Sixty adults having back surgery will be split into two groups: one gets the block before surgery, the other during. The goal is to see which timing lowers opioid use, anesthesia needs, and side effects.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
erector spinae plane block (ESPB) with local anesthetic
What this could lead to
If successful, this could show that giving the nerve block before surgery reduces pain, opioid use, and side effects better than giving it during surgery.
What could go wrong
This is a small, early-phase trial with only 60 participants, so results may not apply to everyone. The block may not work as well as hoped, and there are always risks like infection or allergic reaction.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2025

Expected to finish

Jan 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Those over 18 and under 75 years of age, * Those with an American Society of Anesthesiologists (ASA) score of I-II-III, * Those with a body mass index (BMI) between 18-40 kg/m2 * Patients undergoing surgery with general anesthesia * Patients undergoing LDH surgery (levels 1, 2, and 3) * Patients with informed consent Exclusion Criteria: * Patients with severe cardiovascular system disease, * Patients with coagulation disorders, * Those allergic to the anesthetic and analgesic drugs to be administered, * Patients with infection at the injection site, * Patients with severe renal failure, gastrointestinal ulceration or severe asthma that prevents standard analgesia protocol * Patients who have previously undergone LDH surgery at the same level, * Patients who are planned to have surgery at more than 3 levels * Patients with ASA 4 and above, * Patients who are planned with total intravenous anasthesia(TIVA)

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Conditions

The condition(s) this trial relates to.

lumbar disk herniation, susceptibility to Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Erector spina plan block Opioid consumption Postoperative pain

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Ankara Atatürk Sanatorium Training and Research Hospital

    RECRUITING

    Ankara, Turkey (Türkiye)

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