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New study aims to unlock secrets of pneumonia in the elderly

NCT ID NCT07070284

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at 500 elderly patients (65 and older) with severe pneumonia to understand why some recover and others don't. Researchers will review medical records from hospitals across Europe, focusing on death rates and complications. No new drugs or treatments are being tested—the goal is to learn from real-world data to improve future care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors better predict and manage severe pneumonia in older adults, leading to improved care guidelines.
What could go wrong
This is an observational study, not a treatment trial. It cannot prove that any specific intervention works, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 500 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2025

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Hospitalized patients aged 65 years or older with a clinical and radiological diagnosis of severe community-acquired pneumonia (sCAP). Participants will be enrolled retrospectively from multiple European centers, representing a diverse elderly population. The study includes patients admitted during both epidemic (winter) and non-epidemic (summer) seasons to capture seasonal variations in pathogen distribution and clinical outcomes.

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 65 years-old or older. * Patients with clinically and radiologically (Chest X-Ray (CXR), Computerized Tomography (CT) or lung ultrasound (LUS) confirmed pneumonia. * Patients fulfilling the protocol definition of sCAP Exclusion Criteria: * Age \< 65 years. * Recent hospitalization (above 48 h within the past 10 days) in acute healthcare settings. * Terminal events or imminent death * Patients receiving comfort care only or with documented decisions to forgo intensive medical interventions.

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Conditions

The condition(s) this trial relates to.

Community-Acquired Infections Community-Acquired Pneumonia pneumonia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    18 sites in 6 countries. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • ARNAS Civico-Di Cristina-Benfratelli Hospital - Infectious Diseases Unit

    Palermo, Sicily, 90127, Italy

  • ASST del Garda - Ospedale Civile "La Memoria" di Gavardo

    Gavardo, Lombardy, 25085, Italy

  • Azienda Ospedaliero-Universitaria Pisana

    Pisa, Tuscany, 56126, Italy

  • Azienda Ospedaliero-Universitaria Policlinico Umberto I

    Rome, Lazio, 00161, Italy

  • Azienda Ospedaliero-Universitaria di Modena

    Modena, Emilia-Romagna, 41124, Italy

  • Bellvitge Universitary Hospital

    L'Hospitalet de Llobregat, Barcelona, 08907, Spain

  • Centre Hospitalier Intercommunal Hôpitaux du Pays du Mont-Blanc - Site de Chamonix

    Chamonix, 74400, France

  • Centre Hospitalier de Melun

    Melun, 77000, France

  • Centre hospitalier Alpes Léman

    Contamine-sur-Arve, 74130, France

  • Centro Hospitalar Universitário de São João (CHUSJ)

    Porto, 4200-319, Portugal

  • Corporació Sanitària Parc Taulí

    Sabadell, Catalunuya, 08208, Spain

  • Evangelismos General Hospital

    Athens, 10676, Greece

  • Hospital Universitario Donostia

    Donostia / San Sebastian, Gipuzkoa, 20014, Spain

  • Hospital Universitario Virgen del Rocío

    Seville, Andalusia, 41013, Spain

  • Hospital del Mar Barcelona

    Barcelona, Catalonia, 08003, Spain

  • Hôpital Bichat - Claude-Bernard

    Paris, 75018, France

  • Thibaut Fraisse

    Alès, 30103, France

  • University Hospital for Infectious Diseases Dr. Fran Mihaljević

    Zagreb, City of Zagreb, 10000, Croatia

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