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Tiny study tests nerve block for kidney stone pain

NCT ID NCT05625802

Symptom relief Sponsor: University of Michigan Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a procedure called an erector spinae plane block to see if it could help with pain from kidney stones. Only 5 people took part, all of whom had already received one pain medication in the emergency room. The results are very early and not enough to draw firm conclusions.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Ropivacaine
What this could lead to
If it works, this could offer a new way to manage kidney stone pain in the emergency room.
What could go wrong
This was a very small, early study with only 5 participants. The results may not apply to most people, and the procedure carries risks like infection or bleeding.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

5 people

The number who actually took part.

Started

Feb 2023

Finished

Feb 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Imaging confirmation of urolithiasis on the index encounter or prior encounter within 7 days * Patient received one dose of parenteral pain medication in the emergency department (ED) Exclusion Criteria: * Pregnancy or breastfeeding * Prisoner or incarcerated individual * Therapeutic anticoagulation or coagulopathy. * Active treatment for urinary tract infection (either acute infection or chronic therapy) * Prior spinal surgery in the thoracic region * Allergy to local anesthetic or prior local anesthetic * Soft tissue infection overlying the injection site * Positive for coronavirus * Inability to communicate verbally or read/write in English * Currently taking strong CYP1A2 inhibitor (fluvoxamine, amiodarone, fluoroquinolones, etc.) * Glucose-6-phosphate dehydrogenase deficiency (G6PD)

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Conditions

The condition(s) this trial relates to.

Emergencies Kidney Calculi nephrolithiasis Renal Colic urolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Kidney stone Renal colic

Contacts and locations

Locations

  • The University of Michigan

    Ann Arbor, Michigan, 48109, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.