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Two routes to clear bladder stones: which surgery works better?

NCT ID NCT07810582

Symptom relief Sponsor: Assiut University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 09, 2026 · Last updated Sep 10, 2026 · Updated 1 time

Summary

Researchers compare two minimally invasive operations for adults with bladder stones. One approach, transurethral cystolithotripsy, reaches the bladder through the urethra. The other, percutaneous cystolithotripsy, goes through a small puncture in the lower belly. The trial randomly assigns 50 adults to one of the two procedures and tracks stone clearance, operation time, complications, catheter duration, and hospital stay.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
two minimally invasive surgical procedures for bladder stones: transurethral cystolithotripsy and percutaneous cystolithotripsy
What this could lead to
If one approach proves better, it could give surgeons clearer guidance on which operation to choose for adults with bladder stones.
What could go wrong
This is a small study of 50 people at a single center, so its results may not apply to all patients or hospitals. Both procedures carry risks like bleeding, infection, or incomplete stone removal.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Nov 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients aged 18 years or older * Diagnosed with single or multiple urinary bladder stones * Stone diameter between 1 and 4 cm at its largest diameter or cumulative stone diameter * Candidates for both transurethral and percutaneous endoscopic treatment modalities Exclusion Criteria: * Active urinary tract infection (UTI) * Uncorrected coagulopathy or bleeding disorders * Known urethral stricture or significant urethral pathology precluding safe transurethral instrumentation * History of bladder augmentation, major lower abdominal surgery, or pelvic radiotherapy * Concomitant bladder tumor or suspected bladder neoplasm * Stone located within a bladder diverticulum or within a contracted bladder * Requiring concomitant urological procedures during the same operative session (e.g., transurethral resection of the prostate \[TURP\] or lower ureteric stone extraction) * Urethral stones pushed back into the bladder * Refusal to participate in the study

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Conditions

The condition(s) this trial relates to.

bladder calculus urolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bladder calculi Urinary bladder calculi Urolithiasis

How to take part

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  1. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

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