New combo aims to outsmart resistant breast cancer
NCT ID NCT07198724
First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 24 times
Summary
This study tests whether combining two drugs—elacestrant and trastuzumab deruxtecan—can shrink tumors in people with a certain type of advanced breast cancer (HR+, HER2-low or ultra-low) that has stopped responding to standard hormone therapy and CDK4/6 inhibitors. About 65 participants will receive the combination to find the safest dose and measure how well it works. The goal is to control the disease, not cure it, as ongoing treatment is needed.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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