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New drug shows promise for rare heart condition in chinese patients

NCT ID NCT06194825

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 28 times

Summary

This study tests a drug called eplontersen in Chinese adults with a heart condition caused by a faulty protein (transthyretin amyloid cardiomyopathy). The goal is to see if the drug safely lowers that protein and improves heart health. About 64 participants will receive either eplontersen or a placebo for 24 weeks, then everyone gets the drug for another 80 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Research Site

    Beijing, 100029, China

  • Research Site

    Beijing, 100034, China

  • Research Site

    Beijing, 100037, China

  • Research Site

    Beijing, 100191, China

  • Research Site

    Beijing, 100730, China

  • Research Site

    Changsha, 410008, China

  • Research Site

    Changsha, 410013, China

  • Research Site

    Changsha, 430033, China

  • Research Site

    Chengdu, 610041, China

  • Research Site

    Chengdu, 610072, China

  • Research Site

    Chongqing, 400010, China

  • Research Site

    Chongqing, 400042, China

  • Research Site

    Guangzhou, 510062, China

  • Research Site

    Guangzhou, 510100, China

  • Research Site

    Hangzhou, 310003, China

  • Research Site

    Hangzhou, 310014, China

  • Research Site

    Hangzhou, 310052, China

  • Research Site

    Ha’erbin, 150001, China

  • Research Site

    Jinan, 250001, China

  • Research Site

    Nanchang, 330006, China

  • Research Site

    Shanghai, 200032, China

  • Research Site

    Suzhou, 215006, China

  • Research Site

    Taiyuan, 030001, China

  • Research Site

    Wuhan, 430030, China

  • Research Site

    Wuhan, 430060, China

  • Research Site

    Xi'an, 710061, China

Conditions

Explore the condition pages connected to this study.