Epilepsy Self-Management programs aim to lift mood and quality of life
NCT ID NCT07087821
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two self-management programs (UPLIFT and PACES) against usual care for adults with epilepsy. Researchers will track depression symptoms, quality of life, and seizures over 12 months in 108 participants. The goal is to see if these programs help people manage their condition better and feel less depressed.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 108 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2025
- Expected to finish
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Sep 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults (≥18 years) * English-speaking (UPLIFT and PACES) or Spanish-speaking (UPLIFT only). * Diagnosed with epilepsy for at least one year * Able to understand the informed consent and provide consent * Elevated depressive symptoms - Patient Health Questionnaire-9 (PHQ-9) score ≥10; applies to UPLIFT only Exclusion Criteria: * Severe depressive symptoms (score of ≥20 on PHQ-9) * Active suicidal ideation (score of ≥1 on PHQ-9 item #9 or otherwise reported during screening) * Active psychotic disorder (psychiatric diagnosis and/or antipsychotic medications in the electronic health records (EHR) * Significant cognitive impairment (indicated in the EHR or evident during screening)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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NYU Langone Health - NYU Comprehensive Epilepsy Center
RECRUITINGNew York, New York, 10016, United States
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NYU Langone Health - NYU Langone Hospital-Brooklyn
RECRUITINGBrooklyn, New York, 11220, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can lavender and lullabies help kids with epilepsy sleep better?
- Reading the Brain's signals to predict who benefits from deep brain stimulation
- Can a Comfort-Focused education program improve life with epilepsy?
- Can video games rewire young brains after injury?
- High-Fat Diet's effect on epilepsy: scientists track brain signals
- Epilepsy drug candidate put to the test in healthy volunteers