Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Knee replacement patients may get better pain relief with bolus method

NCT ID NCT07605208

Symptom relief Sponsor: Sakarya University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests two methods of delivering pain medicine through an epidural after total knee replacement. One method gives small, steady doses, while the other gives programmed bursts. The goal is to see which approach provides better pain control and helps patients recover faster. About 90 adults having elective knee surgery will take part.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 90 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 to 80 years * American Society of Anesthesiologists (ASA) physical status I-III * Scheduled for elective primary total knee arthroplasty * Eligible for combined spinal-epidural anesthesia and postoperative epidural analgesia * Able to understand and use patient-controlled epidural analgesia * Provided written informed consent Exclusion Criteria: * Refusal to participate in the study * Known allergy or hypersensitivity to study medications * Body mass index (BMI) ≥ 40 kg/m² * Body weight \< 40 kg * Severe cardiac disease, including symptomatic arrhythmia or advanced conduction abnormalities * Coagulopathy (INR \> 1.5 or platelet count \< 100,000/mm³) * Pregnancy or breastfeeding * Revision total knee arthroplasty or emergency surgery * Active infection at the site of regional anesthesia * Chronic opioid use or opioid dependence * Neurological disease or preexisting motor/sensory deficit in the lower extremities * ASA physical status IV or V * Requirement for intraoperative epidural local anesthetic supplementation due to inadequate spinal anesthesia

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Epidural analgesia are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Epidural analgesia Total knee anthroplasty

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Sakarya University Training and Research Hospital, Department of Anesthesiology and Reanimation

    Sakarya, Adapazari, 54000, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.