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Blood test could reveal how lung cancer evolves during treatment
NCT ID NCT07670442
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study uses blood tests (liquid biopsies) to track how small cell lung cancer changes during chemotherapy and immunotherapy. Researchers will analyze DNA from blood samples taken before, during, and after treatment in 50 patients. The goal is to understand why some cancers become resistant and to guide more personalized treatment in the future.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors personalize lung cancer treatment by tracking how the tumor changes over time.
- What could go wrong
- This is an observational study, not a treatment trial. It may not lead to immediate changes in care, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jul 2026
An estimate. Start dates often move.
- Expected to finish
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Jul 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with SCLC
- Ages
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18 years and older
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Histologically or cytologically confirmed SCLC Indication for first-line systemic anti-tumor treatment with chemo-immunotherapy as decided in a multidisciplinary tumor board. Patient's ability to comply with the required study follow-up. Age ≥ 18 years. Patient affiliated with a social security scheme. Patient managed in the Thoracic Oncology department of Cochin Hospital or HEGP. Patient able to understand the participant information sheet. Exclusion Criteria: Expressed refusal at the time of receiving the information sheet. Person not proficient in the French language. Person deprived of liberty or under legal protection (including guardianship or curatorship). Pregnancy or breastfeeding.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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