New combo aims to boost rectal cancer treatment before surgery
NCT ID NCT03516708
First seen Feb 14, 2026 · Last updated May 24, 2026 · Updated 16 times
Summary
This study tests adding an experimental drug called epacadostat to standard chemotherapy and radiation for people with locally advanced rectal cancer. The treatment is given before surgery to remove the tumor. The goal is to find the best dose and see if the combination improves outcomes. About 49 adults with stage 2 or 3 rectal cancer are being recruited.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Dana Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Henry Ford Cancer Institute
WITHDRAWNDetroit, Michigan, 48202, United States
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University of California Irvine - Chao Family Comprehensive Cancer Center
WITHDRAWNOrange, California, 92868, United States
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Washington University School of Medicine
RECRUITINGSt Louis, Missouri, 63110, United States
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Conditions
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