New combo therapy aims to boost rectal cancer treatment before surgery
NCT ID NCT03516708
First seen Feb 14, 2026 · Last updated May 16, 2026 · Updated 14 times
Summary
This study tests whether adding the drug epacadostat to standard chemotherapy and radiation before surgery can improve outcomes for people with locally advanced rectal cancer. About 49 adults with stage 2 or 3 rectal cancer will take part. The goal is to find the best dose and see if the combination helps shrink tumors more effectively.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Dana Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Henry Ford Cancer Institute
WITHDRAWNDetroit, Michigan, 48202, United States
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University of California Irvine - Chao Family Comprehensive Cancer Center
WITHDRAWNOrange, California, 92868, United States
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Washington University School of Medicine
RECRUITINGSt Louis, Missouri, 63110, United States
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Conditions
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