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Could a simple blood or urine test replace painful biopsies for kids with EoE?

NCT ID NCT03822325

First seen Jun 05, 2026 · Last updated Jun 18, 2026 · Updated 3 times

Summary

This study aims to find non-invasive markers in blood and urine that can show whether inflammation is present in the esophagus of children with eosinophilic esophagitis (EoE). Researchers will compare these markers with tissue samples from biopsies to see if they can reliably detect active disease. The goal is to reduce the need for repeated endoscopies and biopsies in the future. The study involves 88 children aged 1 to 18 who are already scheduled for an upper endoscopy.

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Contacts and locations

Locations

  • Ann & Robert H Lurie Children's Hospital of Chicago

    Chicago, Illinois, 60611, United States

  • University of Illinois at Chicago (UIC)

    Chicago, Illinois, 60612, United States

Conditions

The condition(s) this trial relates to.

eosinophilic esophagitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.