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Massive study probes cancer risk in EoE patients

NCT ID NCT07102329

Knowledge-focused Sponsor: IRCCS San Raffaele Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at 100,000 patient records to find out if people with eosinophilic esophagitis (EoE) are more likely to develop esophageal cancer. The researchers wanted to see if any increased risk is due to EoE itself or to other conditions like acid reflux or Barrett's esophagus. By analyzing real-world data, the study aims to clarify the true cancer risk for EoE patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If this study clarifies the link, it could help doctors better monitor EoE patients for cancer risk.
What could go wrong
This is a retrospective analysis of existing records, not a controlled trial. It can show associations but not prove cause and effect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

100,000 people

The number who actually took part.

Started

Jul 2025

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

\- EoE diagnosed patients according to ICD-10 code K20, compared to control population

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * EoE diagnosed patients according to ICD-10 code K20 Exclusion Criteria: * Patients diagnosed with other EGIDs (- K52.81: Eosinophilic Gastritis or Gastroenteritis * K52.82: Eosinophilic Colitis * K558.4: Eosinophilic gastroenteritis and colitis)

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Conditions

The condition(s) this trial relates to.

Barrett esophagus eosinophilic esophagitis Esophageal Neoplasms gastroesophageal reflux disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Eosinophilic esophagitis (EOE)

Contacts and locations

Locations

  • IRCCS San Raffaele Hospital

    Milan, Lombardy, 20132, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.