Sound waves and gel team up to heal stubborn leg ulcers
NCT ID NCT07626203
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tested a new way to treat venous leg ulcers, which are slow-healing wounds on the lower leg. Researchers used ultrasound to push hyaluronic acid gel into the wound and compared it to standard care in 64 patients. The goal was to see if this combination speeds up healing and reduces wound size.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- hyaluronic acid gel
- What this could lead to
- If it works, this could offer a better way to heal venous leg ulcers faster, reducing pain and recurrence risk.
- What could go wrong
- This is a small, completed trial with only 64 participants, so results may not apply to everyone. The improvement over standard care may be modest or not clinically meaningful.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
64 people
The number who actually took part.
- Started
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Dec 2024
- Finished
-
Feb 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
30 to 70 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients of both genders whose ages were between 30 - 70 years. * Patients with active venous ulcers (C6) according to CEAP (Clinical manifestations- Etiology- Anatomic distribution-Pathophysiology) classification. * clinically proved to be non-infected venous ulcers. * Patients receive the traditional physical therapy management for venous ulcers which includes compression therapy and active exercise plus frequent dressing change. * Patients suffering from recurrent or failed to heal venous ulcers. Exclusion Criteria: * Individuals who were confined to bed with life-threatening conditions that could interfere with the study's objectives, such as myocardial infarction, renal failure or autoimmune diseases. * Patients who had hyaluronic acid hypersensitivity. * Presence of skin disorders or conditions that considered contraindicated for therapeutic US (e.g., cellulitis).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Outpatient Clinics of Faculty of Physical Therapy ,Cairo University.
Giza, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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