Scientists seek clues to predict weight loss success after new stomach procedure
NCT ID NCT05750134
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 116 overweight or moderately obese adults who had a procedure called endoscopic sleeve gastroplasty to help them lose weight. The goal was to find out why some people lose more weight than others after the procedure. Researchers checked blood samples and medical records to see if certain factors could predict weight loss. The study did not test a new treatment but aimed to better understand who benefits most from this procedure.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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116 people
The number who actually took part.
- Started
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Jan 2023
- Finished
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Mar 2023
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with moderate obesity undergoing endoscopic sleeve gastroplasty
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥18 years * Patients giving their consent for the study * Body mass index between 28 and 35 kg/m2 with co-morbid condition (type 2 diabetes, hypertension, dyslipidemia, obstructive sleep apnea, non-alcoholic fatty liver disease or invalidating joint pain) * No weigh loss following life-style changes Exclusion Criteria: * Antibiotic treatment during the three previous months * Patients at risk of gastric cancer requiring regular endoscopic surveillance * Gastric localization of Crohn disease * Portal hypertension * Severe hepatic or renal failure * Ongoing peptic ulcer * Severe associated disease * History of previous bariatric surgery
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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AP-HP, Antoine Béclère Hospital, Department of Hepatology, Gastroenterology, and Nutrition
Clamart, 92140, France
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Other studies related to the condition(s) this trial covers.
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