5,000 women join quest to unravel Endometriosis-Fertility link
NCT ID NCT07558629
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows 5,000 women with and without endometriosis who are undergoing IVF treatment. Researchers will track pregnancy and birth rates, and analyze biological samples to understand how endometriosis affects fertility. The goal is to gather evidence that could lead to better diagnosis and personalized care for affected women.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this research could reveal new insights into why endometriosis harms fertility and point toward better personalized treatments.
- What could go wrong
- This is an observational study, not a treatment trial. It will not directly test any new drug or therapy, and results may take years to translate into clinical practice.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 5,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2025
- Expected to finish
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Jan 2037
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Mainly composed of people from Shandong Province
- Ages
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20 to 37 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with endometriosis and non-endometriosis who are scheduled to undergo in vitro fertilization/ intracytoplasmic sperm injection treatment at our hospital; * Womens' age \<38 year; * Patients diagnosed with endometriosis through surgery, ultrasound or magnetic resonance imaging. Exclusion Criteria: * The patient suffers from a severe uterine leiomyoma or other serious diseases; * The patient previously underwent unilateral/bilateral oophorectomy due to the disease; * The patient was previously diagnosed with a tumor-related disease; * The patients with immune disorders or metabolic diseases; * The patient undergoes egg cell donation; * The patient underwent pre-implantation genetic diagnosis.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The Second Hospital of Shandong University
Jinan, Shandong, 977998, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can Pre-Surgery pelvic floor therapy stop endometriosis pain after the operation?
- Which sperm picking method gives IVF the best shot?
- Appendix: the hidden driver of endometriosis pain?
- Allergy pill put to the test against endometriosis pain
- Can ultrasound and tissue clues reveal which endometriosis lesions carry cancer risk?
- Can AI personalize exercise to ease pelvic pain?