Which surgery helps women with endometriomas get pregnant faster?
NCT ID NCT07119060
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares three surgical treatments for endometriomas (ovarian cysts from endometriosis) in 332 women aged 18-43 who want to become pregnant. Participants are randomly assigned to cystectomy, plasma vaporization, or sclerotherapy. The main goal is to see which approach leads to the highest pregnancy rates within 24 months after surgery, while also tracking birth rates, cyst recurrence, complications, and pain changes.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 332 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2025
- Expected to finish
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Jan 2035
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 43 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient aged between 18 and 43 years (inclusive) * Patient diagnosed with endometriosis (by histology or imaging) and symptomatic, requiring surgery (pelvic pain and/or infertility and/or risk to an organ) * Pelvic MRI or ultrasound performed within the last year showing at least one endometrioma larger than 20 mm in diameter * Patient with an intention to conceive (probable or certain) after surgery * Patient informed and having signed the consent form * Patient covered by a social security scheme Exclusion Criteria: * Intraoperative finding that the cyst is not an endometrioma * Patient under guardianship, conservatorship, or incapable of giving consent * Patient without sufficient understanding of the French language * Patient under judicial protection measures * Patient who is pregnant or breastfeeding
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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IFEMEndo - Clinique Tivoli
RECRUITINGBordeaux, 33000, France
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