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Higher radiation doses tested for elderly brain cancer patients

NCT ID NCT06835803

First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 40 times

Summary

This study tests whether a higher daily dose of radiation over three weeks can improve survival for people aged 65 and older with newly diagnosed glioblastoma, an aggressive brain cancer. Participants will be randomly assigned to receive either the standard radiation dose or an escalated dose. The trial aims to find a better balance between effectiveness and quality of life in this older population.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Brigham and Women's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Dana-Farber Brigham Cancer Center, Milford Hospital

    RECRUITING

    Milford, Massachusetts, 01757, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Dana-Farber Brigham Cancer Center, South Shore Hospital

    RECRUITING

    South Weymouth, Massachusetts, 02190, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

radiation therapy

What this could lead to

If it works, this could offer a more effective radiation schedule for older glioblastoma patients, potentially extending survival without lengthening treatment time.

What could go wrong

This is a small, early-phase trial with only 56 participants. Higher radiation doses may increase side effects, and the benefit over standard care is not yet proven.

Conditions

The condition(s) this trial relates to.

glioblastoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.