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Can acupuncture replace painkillers for facial nerve pain?

NCT ID NCT06977932

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether electroacupuncture (a type of acupuncture with mild electric pulses) can reduce pain in people with trigeminal neuralgia, a condition causing severe facial pain. 126 participants will either get real electroacupuncture or a sham version, while continuing their usual medication. The goal is to see if electroacupuncture can offer a safer alternative to carbamazepine, which can cause addiction and other side effects.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
electroacupuncture
What this could lead to
If it works, this could offer a drug-free option to manage trigeminal neuralgia pain with fewer side effects.
What could go wrong
This is a small, early-stage trial with only 126 participants. The sham acupuncture group may also show some benefit, making it hard to prove real effect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 126 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Mar 2026

An estimate. Start dates often move.

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Diagnostic Criteria Diagnosis was based on the criteria for trigeminal neuralgia (TN) as defined in the third edition of the International Classification of Headache Disorders (ICHD-3) published by the International Headache Society (IHS) in 2018. The diagnostic criteria included: 1. recurrent unilateral facial pain occurring in the distribution of one or more divisions of the trigeminal nerve, without radiation outside the trigeminal territory, and meeting criteria (2) and (3); 2. pain presenting with all of the following characteristics: ① paroxysmal attacks lasting from a few seconds to 2 minutes; ② severe intensity; * electric shock-like, stabbing, or sharp quality; 3. pain triggered by innocuous stimuli within the affected trigeminal distribution; 4. exclusion of other facial pain disorders classified in ICHD-3. Inclusion Criteria All of the following criteria had to be met for study enrollment: * fulfillment of the TN diagnostic criteria as stated above; * age between 18 and 80 years, inclusive, irrespective of sex; * receiving a stable daily dose of carbamazepine (200-400 mg); ④ consciousness clear, with intact pain perception and discrimination, and able to communicate effectively; ⑤ voluntary participation with written informed consent provided by the patient or their legal guardian/authorized representative. Exclusion Criteria Participants were excluded if they met any of the following: * comorbid epilepsy, head injury, or other relevant neurological disorders; * significant impairment of cardiac, hepatic, or renal function; * cognitive dysfunction, aphasia, psychiatric conditions, or inability to cooperate with treatment; * poorly controlled hypertension or hyperglycemia; ⑤ recent diagnosis of severe anxiety or depression; ⑥ pregnancy or lactation; ⑦ presence of a cardiac pacemaker or other contraindications to electroacupuncture therapy; ⑧ current participation in another clinical trial.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

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