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Could a common drug help fight rare bone cancers?

NCT ID NCT07321912

First seen Jan 11, 2026 · Last updated Jun 12, 2026 · Updated 26 times

Summary

This study tests whether adding eflornithine (DFMO) to standard chemotherapy can help teens and young adults with Ewing sarcoma or osteosarcoma live longer without their cancer coming back. About 406 participants will join one of five groups based on their cancer type and stage. The goal is to see if this added treatment improves survival and is safe.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Penn State Milton S. Hershey Medical Center and Children's Hospital

    RECRUITING

    Hershey, Pennsylvania, 17033, United States

    Contact Email: •••••@•••••

    Contact

  • St. Joseph's Children's Hospital

    RECRUITING

    Tampa, Florida, 33614, United States

    Contact

    Contact Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

Ewing sarcoma osteosarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.