Lung cancer drug interaction study: does itraconazole boost AZD9291 levels?
NCT ID NCT02157883
First seen Nov 19, 2025 · Last updated May 22, 2026 · Updated 25 times
Summary
This study looked at how the antifungal drug itraconazole changes the amount of AZD9291 in the blood of people with a specific type of advanced lung cancer (EGFR mutation-positive NSCLC) that stopped responding to previous treatments. Thirty-nine adults took a single dose of AZD9291 with and without itraconazole to measure drug levels. The goal was to understand potential drug interactions, not to test the treatment's effectiveness.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Research Site
San Diego, California, 92123, United States
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Research Site
Cleveland, Ohio, 44106, United States
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Research Site
Edegem, 2650, Belgium
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Ghent, 9000, Belgium
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Research Site
Amsterdam, 1066 CX, Netherlands
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Research Site
Maastricht, 6229 HX, Netherlands
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Research Site
Rotterdam, 3015 GD, Netherlands
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Research Site
lJongno-gu, 03080, South Korea
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Research Site
Seongnam-si, 13620, South Korea
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Research Site
Seoul, 03722, South Korea
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Research Site
Seoul, 05505, South Korea
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Research Site
Seoul, 06351, South Korea
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Research Site
Taipei, 10002, Taiwan
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Research Site
Taipei, 11217, Taiwan
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Research Site
London, SE1 9RT, United Kingdom
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Research Site
Manchester, M20 4BX, United Kingdom
Conditions
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