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Can a brain wave reading reveal who benefits from spinal cord stimulation?

NCT ID NCT07820657

Symptom relief Sponsor: Walton Centre NHS Foundation Trust Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 15, 2026 · Last updated Sep 16, 2026 · Updated 1 time

Summary

Researchers at the Walton Centre test whether a shift in a specific brain wave pattern, called theta power, can show which patients with chronic neuropathic leg or back pain respond to spinal cord stimulation. The study enrolls 23 adults with failed back surgery syndrome who are already scheduled for a spinal cord stimulation trial. Participants receive three different stimulation modes in turn, and researchers record EEG brain activity at each stage to see whether theta power tracks with pain relief and whether it can guide which stimulation setting fits each person.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
spinal cord stimulation, a device that sends electrical pulses to the spinal cord to ease pain
What this could lead to
If it works, doctors could use a simple brain wave reading to tell early whether spinal cord stimulation is helping a patient, and which stimulation setting suits them best.
What could go wrong
This is a small pilot study of 23 people with one specific pain condition, so the brain wave signal may not hold up in larger groups or other patients. Spinal cord stimulation itself carries risks such as infection, lead movement, or discomfort.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

23 people

The number who actually took part.

Started

Jun 2022

Finished

Aug 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults (Aged 18 years or above and able to consent) with failed back surgery syndrome leading to neuropathic leg/back pain deemed suitable for spinal cord stimulation trial Exclusion Criteria: * Patients with history of epilepsy or epileptiform disorders

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic neuropathic pain

Contacts and locations

Locations

  • The Walton Centre NHS Foundation Trust

    Liverpool, Merseyside, L97LJ, United Kingdom

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