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Can a headband spot Alzheimer's? new study tests brain wave device

NCT ID NCT05673759

Diagnosis Sponsor: Boston University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a wearable EEG device can help doctors diagnose Alzheimer's disease and mild cognitive impairment. Researchers compared brain wave data from the EEG with standard memory and thinking tests in 148 participants. The goal was to see if the EEG could improve diagnostic accuracy and be easily used in clinics.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could give doctors a simple, non-invasive tool to improve diagnosis of memory problems.
What could go wrong
The study was terminated early, so results are limited. The EEG is not intended to treat or cure any disease.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

148 people

The number who actually took part.

Started

Mar 2023

Finished

May 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Any participant age: 20-90 years old, with or without a diagnosis of AD or cognitive impairment.

Ages

20 to 90 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: For Mild Alzheimer Disease (AD) dementia * Meets probable AD dementia National Institute on Aging and Alzheimer's Association (NIA-AA) criteria * 50-90 years old * Mini-Mental State Examination (MMSE) 20-27 * Performance on delayed recall and recognition memory worse than 1.5 standard deviation (SD) for age and education * Performance on delayed recall and recognition memory worse than 1.5 SD for age \& education in at least one other cognitive domain (e.g., language, executive functioning) based on other tests in our neuropsychological test battery. * Dr. Turk and Dr. Budson will confirm all mild AD dementia diagnoses For Mild cognitive impairment (MCI) * MCI due to any etiology 50-90 years old * MMSE \> 23 * Performance on delayed recall and recognition memory worse than 1.0 SD for age \& education adjusted norms * Dr. Turk and Dr. Budson will confirm all MCI diagnoses For Healthy older adults * 50-90 years old * Functioning normally in occupation determined by self-report For Healthy younger adults * 20-50 years old * Functioning normally in occupation determined by self-report Exclusion Criteria: A clinically significant problem of any of the following conditions: * depression * heavy alcohol or drug use * cerebrovascular disease * a different degenerative disease (e.g., fronto-temporal dementia, Parkinson's disease) * any medical condition whose severity could significantly impair cognition (e.g., organ failure) * on any antipsychotic or epilepsy medication * Unable to understand the consent form

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Conditions

The condition(s) this trial relates to.

Alzheimer disease Cognitive Dysfunction dementia follicular lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alzheimer disease Dementia, mild Mild cognitive impairment

Contacts and locations

Locations

  • BU Alzheimer Disease Center

    Boston, Massachusetts, 02118, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.