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ER program aims to curb opioid use and keep patients in treatment

NCT ID NCT05327166

Disease control Sponsor: University of Washington Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a program called ED-LINC that starts in the emergency room for people with opioid use disorder. The program offers overdose education, motivation to seek help, help choosing medication, and three months of follow-up care. Researchers want to see if this approach reduces illicit opioid use, gets more people on medication, and cuts down on ER visits compared to usual care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Collaborative care program (ED-LINC) including overdose education, motivation counseling, medication decision support, and 3 months of care management
What this could lead to
If it works, this could provide a practical, scalable way to help people with opioid use disorder reduce their drug use and stay engaged in treatment after an ER visit.
What could go wrong
This is a single-site trial with 500 participants, so results may not apply everywhere. The program is complex and may not be easy to adopt in other hospitals.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 500 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2022

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged 18 years or older * Moderate or Severe OUD based on the Structured Clinical Interview for DSM Disorders (SCID) * Currently have a phone or method of contact * Able to provide a phone number and one additional piece of contact information Exclusion Criteria: * Incarcerated or under arrest * Non-English speaking * Live beyond a 50 mile radius of Harborview Medical Center * Require active resuscitation in the ED or other clinical area at the time of Research Assistant (RA) approach * Are receiving palliative care services or hospice care for a chronic illness such as metastatic cancer * Are in the ED or hospital for a primary psychiatric emergency such as suicidal ideation or attempt and require emergent evaluation by a Psychiatrist * Receiving chronic opioid therapy (COT) defined as prescription opioids for most days out of the last 90 days for a chronic pain condition * In the ED for sexual assault * Enrolled or eligible for state-funded or hospital-funded care coordination program based on high utilization of the ED

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Conditions

The condition(s) this trial relates to.

opiate dependence substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Opioid use disorder

Contacts and locations

Locations

  • Harborview Medical Center

    Seattle, Washington, 98104, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.