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Could ultrasound replace X-Rays in heart valve surgery?

NCT ID NCT07317804

First seen Jan 09, 2026 · Last updated Jun 19, 2026 · Updated 23 times

Summary

This study tests whether using only ultrasound (echocardiography) to guide a minimally invasive heart valve replacement is as effective as the standard method that combines X-ray and ultrasound. The goal is to reduce kidney injury from contrast dye and lower radiation exposure. About 212 patients aged 70+ with severe aortic stenosis will be randomly assigned to one of the two guidance methods.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Chinese Academy of Medical Sciences, Fuwai Hospital, Beijing

    Beijing, Beijing Municipality, 100037, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Echocardiographic guidance (ultrasound) vs fluoroscopic guidance (X-ray) during TAVR procedure

What this could lead to

If successful, echo-only guidance could become a safer alternative for TAVR, reducing kidney damage and radiation exposure for patients.

What could go wrong

This is a Phase 4 trial with 212 participants, so results may not apply to all patients. Echo-only guidance may be less precise in some cases, potentially affecting valve placement.

Conditions

The condition(s) this trial relates to.

aortic valve stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.