New blood test could predict pancreatic cancer return
NCT ID NCT07448376
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at a new way to detect cancer cells in the portal vein blood of people with pancreatic cancer. The goal is to see if these cells can warn early if the cancer comes back or spreads. The study will involve 20 participants and uses a special ultrasound-guided procedure to collect blood samples.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a new way to predict if pancreatic cancer will come back or spread, helping doctors choose better treatments earlier.
- What could go wrong
- This is a very small, early-stage exploratory study with only 20 participants. The method is still experimental and may not prove useful in routine care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 20 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Mar 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with pancreatic cancer from Tongji Hospital, Wuhan, scheduled for ultrasound-guided fine-needle aspiration biopsy
- Ages
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18 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Patients with solid masses (diameter \> 1 cm) in the pancreatic area within the accessible range of endoscopic ultrasound, as indicated by clinical symptoms, laboratory tests, and imaging examinations (MRI, CT, B-ultrasound), who require biopsy to clarify the nature of the lesion. 2. Patients diagnosed with resectable pancreatic cancer, borderline resectable pancreatic cancer, locally advanced pancreatic cancer by imaging(CT/MRI). 3. Newly diagnosed pancreatic cancer patients who have not received radiotherapy or chemotherapy. 4. Signed informed consent form. 5. Patients must be able to comply with the trial requirements. Exclusion Criteria: 1. Patients with other active malignant tumors 2. Patients with coagulation dysfunction (PLT 50,000/mm3, INR \> 1.5; roughly estimated, INR \> 1.5 is approximately equivalent to PT \> 18 seconds) 3. Pregnant women 4. Patients with hemorrhagic diseases 5. Patients with a history of taking anticoagulant drugs such as aspirin and warfarin in the past week 6. Patients with absolute contraindications to EUS examination, a history of acute pancreatitis within the past 2 weeks, a history of gastric surgery, pregnancy, severe diseases, or a history of allergy to anesthetics 7. Patients whose EUS examination was terminated early due to esophageal stenosis, obstruction, large space-occupying lesions, rapid changes in the patient's heart rate or respiratory rate, patient intolerance, or a large amount of food residue, etc. 8. Patients with known hepatitis C virus infection 9. Patients with known human immunodeficiency virus (HIV) infection 10. Patients with imaging examinations, EUS results, etc., suggesting pancreatic cystic space-occupying lesions 11. Patients who have received radiotherapy or chemotherapy 12. Patients with incomplete pathological information, unable to make a clear diagnosis, or unable to sign the informed consent form
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Tongji Hospital, Tongji Medical College, HUST
Wuhan, Hubei, 430030, China
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Other studies related to the condition(s) this trial covers.
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