Race against time: new sepsis treatment trial tests immediate medication vs. standard fluids
NCT ID NCT05179499
Summary
This study compares two emergency approaches for treating septic shock, a life-threatening reaction to infection. Researchers want to know if giving blood pressure medication immediately upon hospital arrival works better than the current standard of starting with intravenous fluids first. The trial involves about 1,000 adult patients with severe sepsis and low blood pressure to see which method helps people recover faster, reduces complications, and shortens hospital stays.
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Contacts and locations
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Addenbrookes Hospital, Cambridge
RECRUITINGCambridge, United Kingdom
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Aintree University Hospital
RECRUITINGAintree, United Kingdom
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Fairfield General Hospital
RECRUITINGBury, United Kingdom
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Glasgow Royal Infirmary
RECRUITINGGlasgow, United Kingdom
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Hull Royal Infirmary
RECRUITINGHull, United Kingdom
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John Radcliffe Hospital
RECRUITINGOxford, United Kingdom
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Kettering General
RECRUITINGKettering, United Kingdom
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Leicester Royal Infirmary
TERMINATEDLeicester, United Kingdom
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Newham University Hospital
RECRUITINGLondon, United Kingdom
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Peterborough City Hospital
RECRUITINGPeterborough, United Kingdom
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Queen Elizabeth University Hospital
RECRUITINGGlasgow, United Kingdom
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Queens Hospital Barking
RECRUITINGRomford, United Kingdom
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Royal Alexandra Hospital
RECRUITINGPaisley, United Kingdom
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Royal Berkshire Hospital
RECRUITINGReading, United Kingdom
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Royal Blackburn Hospital
TERMINATEDBlackburn, United Kingdom
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Royal Derby Hospital
RECRUITINGDerby, United Kingdom
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Royal Infirmary of Edinburgh
RECRUITINGEdinburgh, United Kingdom
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Royal Liverpool University Hospital
RECRUITINGLiverpool, United Kingdom
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Royal London Hospital
RECRUITINGLondon, United Kingdom
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Salford Royal
RECRUITINGSalford, United Kingdom
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St George's
TERMINATEDLondon, United Kingdom
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University Hospital Crosshouse
TERMINATEDKilmarnock, United Kingdom
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University Hospital Lewisham
RECRUITINGLondon, United Kingdom
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University Hospital Monklands
RECRUITINGLanark, United Kingdom
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Victoria Hospital
RECRUITINGFife Keith, United Kingdom
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Conditions
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