Can a quick online therapy stop PTSD before it starts?
NCT ID NCT06592677
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether an online, therapist-guided therapy called CIPE can prevent PTSD in people who recently experienced a traumatic event. About 360 adults receiving support from crisis teams will either get CIPE plus usual care or usual care alone. The goal is to see if early online therapy reduces PTSD symptoms and prevents the disorder from developing.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Condensed Internet-delivered Prolonged Exposure (CIPE) - an online, therapist-assisted therapy
- What this could lead to
- If it works, this could provide an effective early intervention to prevent PTSD after a traumatic event, reducing long-term suffering and healthcare costs.
- What could go wrong
- This is a relatively small trial (360 people) testing a new approach. The therapy may not be more effective than usual care, and results may not apply to all trauma survivors.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 360 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2024
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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16 to 99 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Receives support from a municipal crisis team * Exposure to a traumatic event (as defined by criteria A for the diagnosis of post-traumatic stress disorder (PTSD) in the DSM-5) within the last seven weeks before randomization * A total score of 10 or above on the PTSD Symptom Checklist-5 at the time of randomization * Age 16 or above * Written informed consent * Writes and speaks English and/or Norwegian Exclusion Criteria: * Severe psychopathology in need of specialized health care (e.g., psychotic symptoms, or high suicide risk) or substance dependence syndrome in need of specialized health care * Known or evident severe cognitive impairment * Ongoing traumatization, violence, or threats * Unstable dose of psychotropic medication two weeks prior to randomization * Concurrent therapy elsewhere before randomization
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Get notified about this study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
29 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Asker municipality - Psychosocial crisis team
RECRUITINGAsker, Asker, 1384, Norway
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Aurskog-Høland - Psychosocial crisis team
RECRUITINGBjørkelangen, Norway
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Fredrikstad municipality - Psychosocial Crisis team
RECRUITINGFredrikstad, Norway
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Gjerdrum - psychosocial crisis team
RECRUITINGSørum, Norway
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Gjøvik municipality - psychosocial crisis team
RECRUITINGGjøvik, Norway
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Halden Municipality - psychosocial crisis team
RECRUITINGHalden, Norway
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Hamar Municipality - psychosocial crisis team
RECRUITINGHamar, Norway
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Nannestad municipality - psychosocial crisis team
RECRUITINGTeigebyen, Norway
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Norwegian Center for Violence and Traumatic Stress Studies
RECRUITINGOslo, Oslo, 0484, Norway
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Psychosocial crisis team - Indre Østfold kommune
RECRUITINGAskim, Askim, 1830, Norway
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Psychosocial crisis team - Oslo, Alna
RECRUITINGOslo, Oslo, 1051, Norway
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Psychosocial crisis team - Oslo, Bjerke
RECRUITINGOslo, Norway
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Psychosocial crisis team - Oslo, Frogner
RECRUITINGOslo, Norway
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Psychosocial crisis team - Oslo, Grorud
RECRUITINGOslo, Oslo, 0954, Norway
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Psychosocial crisis team - Oslo, Grünerløkka
RECRUITINGOslo, Norway
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Psychosocial crisis team - Oslo, Nordre Aker
RECRUITINGOslo, Oslo, 0484, Norway
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Psychosocial crisis team - Oslo, Nordstrand
RECRUITINGOslo, Norway
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Psychosocial crisis team - Oslo, Sagene
RECRUITINGOslo, Norway
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Psychosocial crisis team - Oslo, St Hanshaugen
RECRUITINGOslo, Oslo, 0170, Norway
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Psychosocial crisis team - Oslo, Stovner
RECRUITINGOslo, Norway
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Psychosocial crisis team - Oslo, Søndre Nordstrand
RECRUITINGOslo, Oslo, 1203, Norway
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Psychosocial crisis team - Oslo, Ullern
RECRUITINGOslo, Oslo, 0377, Norway
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Psychosocial crisis team - Oslo, Vestre Aker
RECRUITINGOslo, Oslo, 0754, Norway
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Psychosocial crisis team - Oslo, gamle Oslo
RECRUITINGOslo, Norway
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Psychosocial crisis team - Oslo, Østensjø
RECRUITINGOslo, Oslo, 0694, Norway
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Psychosocial emergency service - Oslo emergency room
RECRUITINGOslo, Norway
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Ringsaker municipality - Psychosocial crisis team
RECRUITINGRingsaker, Norway
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Søndre Land municipality - psychosocial crisis team
RECRUITINGHov, Norway
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Ullensaker municipality - psychosocial crisis team
RECRUITINGJessheim, Norway
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Five sessions to quiet trauma nightmares in bipolar disorder
- Can training hospital staff in Trauma-Informed care make childbirth safer?
- Scientists probe brain's reward system in mental illness
- Can a mindfulness class help veterans with concussion and PTSD?
- Can MDMA plus therapy help veterans fight both PTSD and alcohol addiction?
- Can talk therapies quiet the trauma of violence?