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Hormone clues may explain why Prader-Willi babies go from feeding struggles to obesity

NCT ID NCT02529085

First seen Apr 11, 2026 · Last updated May 23, 2026 · Updated 7 times

Summary

This study followed 215 infants with Prader-Willi syndrome and a control group to measure hormones that control appetite and growth during the first four years of life. The goal was to understand why children with PWS switch from poor feeding in infancy to extreme hunger and obesity later. No treatments were tested; instead, researchers collected blood samples to build a resource for future studies.

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Contacts and locations

Locations

  • Department of Endocrinology / University Children's Hospital

    Essen, Germany

  • Department of Pediatrics / Division of Endocrinology

    Toulouse, Haute-Garonne, 31000, France

  • Department of Pediatrics / Division of Endocrinology / Erasmus University Medical Center / Sophia Children's Hospital Rotterdam

    Rotterdam, 3015 GJ, Netherlands

  • Karolinska University Hospital

    Stockholm, Sweden

  • Metabolic & Molecular Imaging Group / MRC Clinical Sciences Centre / Imperial College London / Hammersmith Hospital

    London, W12 0NN, United Kingdom

  • Unité d'Endocrinologie Pédiatrique / Université Catholique de Louvain

    Brussels, 1200, Belgium

Conditions

Explore the condition pages connected to this study.