Hormone clues may explain why PWS babies go from feeding trouble to obesity

NCT ID NCT02529085

First seen Apr 11, 2026 · Last updated Apr 24, 2026 · Updated 2 times

Summary

This study followed 215 infants with Prader-Willi syndrome (PWS) and a control group to track how hormones that control appetite and feeding change during the first four years of life. The goal was to understand why babies with PWS start with feeding difficulties and later develop constant hunger and obesity. No treatment was tested; the study only measured hormone levels and stored blood samples for future research.

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Contacts and locations

Locations

  • Department of Endocrinology / University Children's Hospital

    Essen, Germany

  • Department of Pediatrics / Division of Endocrinology

    Toulouse, Haute-Garonne, 31000, France

  • Department of Pediatrics / Division of Endocrinology / Erasmus University Medical Center / Sophia Children's Hospital Rotterdam

    Rotterdam, 3015 GJ, Netherlands

  • Karolinska University Hospital

    Stockholm, Sweden

  • Metabolic & Molecular Imaging Group / MRC Clinical Sciences Centre / Imperial College London / Hammersmith Hospital

    London, W12 0NN, United Kingdom

  • Unité d'Endocrinologie Pédiatrique / Université Catholique de Louvain

    Brussels, 1200, Belgium

Conditions

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