New screening tool aims to catch diabetic nerve damage early
NCT ID NCT07163000
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests a short questionnaire called ACT to see if it can accurately detect nerve damage in the feet and legs of people with diabetes. Researchers will compare it to standard screening tools and an eye test that looks at tiny nerve fibers. The goal is to find a simple, non-invasive way to diagnose peripheral neuropathy earlier.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- ACT questionnaire
- What this could lead to
- If successful, this could provide a simple, low-cost way to catch diabetic nerve damage earlier, helping prevent complications.
- What could go wrong
- This is a small, early-stage validation study, not a treatment trial. The questionnaire may not prove accurate enough for widespread use.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
150 people
The number who actually took part.
- Started
-
May 2025
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Participants attending the outpatients clinic at the diabetes center
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with diabetes (T1DM and T2DM) * Age ≥18 * Able to provide consent. * Able to sit still for corneal confocal microscopy Exclusion Criteria: * Failure to provide informed consent * Participants with a history of ocular trauma or previous ocular surgery in the preceding 6 months, are allergic to oxybuprocaine or local anesthetics or unable to cooperate by holding still or placing their chin on an optical device * Other causes of peripheral neuropathy: vitamin B12 deficiency; hypothyroidism; myeloma. * Cognitively impaired participants * Pregnant women * Nursing women
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Weill Cornell Medicine-Qatar
Doha, 24144, Qatar
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Other studies related to the condition(s) this trial covers.
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