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Video game aims to boost brain power in MS patients

NCT ID NCT04694534

Symptom relief Sponsor: Lille Catholic University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests whether playing a special online game for 20 minutes, four times a week, can improve memory and thinking speed in people with multiple sclerosis. Researchers will compare the game group to a control group receiving standard care. The trial aims to enroll 150 adults with relapsing-remitting or progressive MS who have cognitive complaints.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
serious game (online cognitive training program)
What this could lead to
If it works, this could offer a fun, accessible way to help people with multiple sclerosis sharpen their memory and thinking speed.
What could go wrong
This is an early-stage trial with no phase, so results are uncertain. The game may not provide lasting benefits beyond standard care, and improvements might be small.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 150 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2021

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Relapsing-remitting or progressive multiple sclerosis people defined according to Mc Donald's criteria revised in 2005 * Age between ≥ 18 and ≤ 65 years old * Cognitive complaint, with at least one deficient score at the initial neuropsychological examination (\<5th percentile of the reference group), one of the scores of which concerns at least one BICAMS test * Have not had a definite relapse for at least 6 weeks * Be at least 4 weeks away from a corticosteroid bolus * Lack of neuroleptic treatment * Patient with an Internet connection * Signed informed consent Exclusion Criteria: * Severe cognitive deficit defined by obtaining a deficit score in more than six cognitive processes at the initial neuropsychological assessment. * Neuropsychological care * Inability to receive oral and written information * Inability to use the software (due in particular to motor and / or sensory difficulties), * Neurological or psychiatric comorbidity, other than MS and anxiodepressive syndrome * Patient with severe anxiodepressive syndrome (BDI\> 27) * Participation in an interventional study on cognitive functions * Patient under legal protection, guardianship or curatorship * Pregnant or breastfeeding women

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Conditions

The condition(s) this trial relates to.

learning disability multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Learning MEMORY Multiple sclerosis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    6 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • CH Arras

    RECRUITING

    Arras, Hauts-de-France, 62000, France

  • CH LENS

    RECRUITING

    Lens, Hauts-de-France, 62300, France

  • CHRU

    RECRUITING

    Lille, Hauts-de-France, 59000, France

  • Charles Nicolle Hospital

    RECRUITING

    Rouen, Normandy, 76000, France

  • Saint Vincent hospital

    RECRUITING

    Lille, Hauts-de-France, 59000, France

  • Saint-Philibert hospital

    RECRUITING

    Lomme, Nord, 59462, France

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