Could your gut bacteria shape your mood after cancer surgery?
NCT ID NCT02970513
First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time
Summary
This study looks at whether having certain E. coli bacteria in the colon after colorectal cancer surgery is linked to anxiety or depression. Researchers will compare psychiatric symptoms and diagnoses between patients who carry the bacteria and those who do not. The goal is to better understand any connection between gut bacteria and mental health in this group.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If a link is found, it could point toward new ways to support mental health in colorectal cancer patients, possibly through gut bacteria.
- What could go wrong
- This is a very small study (12 people) and only looks for an association, not proof of cause. Many other factors could explain any differences in mood.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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12 people
The number who actually took part.
- Started
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Mar 2017
- Finished
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Oct 2017
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * patients operated on for colorectal cancer in the digestive surgery department of Clermont-Ferrand hospital * patients older than 18 years, * patients whose Escherichia coli colonization was analyzed after surgery * patients which are always followed by the digestive surgery department. Exclusion Criteria: * Patients with dementia will not be included, according to the MMSE score: * 22 if no grade * 23 if study certificate or CAP or college without patent * 25 if patent or school without the tray * 26 or more when bin
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU Clermont-Ferrand
Clermont-Ferrand, 63003, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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