New study aims to find the best Weight-Loss surgery for fewer side effects
NCT ID NCT07263269
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two types of weight-loss surgery—sleeve gastrectomy alone versus sleeve gastrectomy with transit bipartition—to see which leads to fewer cases of dumping syndrome (nausea, diarrhea, dizziness after eating) and better quality of life. Researchers will follow 200 adults with obesity for six months after surgery, using questionnaires and medical checks. The goal is to help patients and doctors choose the procedure with the best balance of weight loss and comfort.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Sleeve gastrectomy with or without transit bipartition (surgical procedures)
- What this could lead to
- If successful, this study could help surgeons choose the better surgical technique to reduce uncomfortable dumping symptoms and improve quality of life after weight-loss surgery.
- What could go wrong
- This is a small, early-stage comparative study with only 200 participants and a short 6-month follow-up. Results may not apply to all patients, and the added procedure could carry its own risks.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 200 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2024
- Expected to finish
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Mar 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 65 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * BMI exceeding 40 kg/m2 * BMI exceeding 35 kg/m2, when diagnosed with obesity-related diseases, including type 2 diabetes, hypertension, lipid disorders, and obstructive sleep apnea. * Obtain informed written consent from the patients or their first guardians * Patients choosing LSG or LSTB after being offered all suitable bariatric procedures Exclusion Criteria: * Patients or their first guardians refusing to participate in the current study. * Previous bariatric surgeries
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Faculty of Medicine Cairo University
Cairo, Egypt
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Other studies related to the condition(s) this trial covers.
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