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Can a Cannabis-Like drug cut opioid use after knee surgery?

NCT ID NCT04734080

First seen Apr 02, 2026 · Last updated May 24, 2026 · Updated 10 times

Summary

This study tested whether dronabinol, a drug similar to cannabis, can help reduce the need for opioid painkillers after knee replacement surgery. 114 adults were randomly assigned to receive either dronabinol or a placebo before and after surgery. Researchers measured opioid use, pain levels, and recovery time to see if dronabinol offered any benefit.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Hospital for Special Surgery

    New York, New York, 10021, United States

Conditions

Explore the condition pages connected to this study.