Pain patients put to the test: can you drive on opioids?
NCT ID NCT00659035
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study uses a driving simulator to test whether people with chronic pain can drive safely while taking oral opioids. 450 participants with a valid driver's license will be tested on measures like weaving and reaction time. The goal is to provide better guidance to patients and doctors about driving restrictions.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- oral opioids
- What this could lead to
- If successful, this could provide evidence to help doctors give more personalized advice about driving while on pain medication.
- What could go wrong
- This is an observational study using a simulator, not real driving. Results may not reflect actual road safety, and the study is not testing a new treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 450 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Apr 2008
- Expected to finish
-
Dec 2026
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Pain Clinic population
- Ages
-
18 to 80 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Driving license Exclusion Criteria: * Any other drug or condition that would impair driving ability * History of seizures
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Rush University Medical Center
Chicago, Illinois, 60612, United States
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Other studies related to the condition(s) this trial covers.
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