Pain patients put to the test: can you drive on opioids?

NCT ID NCT00659035

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study uses a driving simulator to test whether people with chronic pain can drive safely while taking oral opioids. 450 participants with a valid driver's license will be tested on measures like weaving and reaction time. The goal is to provide better guidance to patients and doctors about driving restrictions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
oral opioids
What this could lead to
If successful, this could provide evidence to help doctors give more personalized advice about driving while on pain medication.
What could go wrong
This is an observational study using a simulator, not real driving. Results may not reflect actual road safety, and the study is not testing a new treatment.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Rush University Medical Center

    Chicago, Illinois, 60612, United States

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