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Could a simple Height-Based adjustment make tumor ablation safer?

NCT ID NCT07408375

Knowledge-focused Sponsor: Nantes University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how to set the breathing machine (jet ventilator) during a procedure that destroys tumors with heat or cold. The goal is to find the best air pressure setting to keep patients breathing well while the doctor works precisely. About 560 adults having tumor ablation will be randomly assigned to one of four pressure settings, including one based on their height. The study will compare how often breathing problems occur with each setting.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 560 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2026

Expected to finish

Mar 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 18 years. * Patient undergoing thermal ablation of a solid tumor under HFJV. * Patient who has given their consent. * Patient covered by a social security scheme. Exclusion Criteria: * Patient under guardianship or curatorship. * Patient who does not understand French. * Pregnant and breastfeeding woman * Patient who has had a pneumonectomy * Patient requiring an endotracheal tube smaller than 6.5

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Conditions

The condition(s) this trial relates to.

neoplasm Respiratory Aspiration

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Solid tumor (excluding CNS)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    7 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • CHU de Lyon

    NOT_YET_RECRUITING

    Lyon, 69002, France

  • CHU de Nantes

    RECRUITING

    Nantes, 44093, France

  • CHU de Nîmes

    NOT_YET_RECRUITING

    Nîmes, 30900, France

  • CHU de Poitiers

    NOT_YET_RECRUITING

    Poitiers, 86000, France

  • Centre Léon Bérard

    NOT_YET_RECRUITING

    Lyon, 69008, France

  • ICO Unicancer

    NOT_YET_RECRUITING

    Saint-Herblain, 44800, France

  • Institut Gustave Roussy

    RECRUITING

    Villejuif, 94800, France

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