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15-Year study to uncover immune secrets in down syndrome

NCT ID NCT07416201

First seen Feb 19, 2026 · Last updated May 17, 2026 · Updated 15 times

Summary

This study follows 700 people with Down syndrome (and some healthy relatives) for up to 15 years to understand how their immune system changes over time. Researchers will check for infections, autoimmune problems, and cancers, and see if having part of the thymus removed during heart surgery makes a difference. Participants give blood, stool, and have heart and lung tests at yearly visits.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.