New study prepares adults with down syndrome for Alzheimer's trials
NCT ID NCT04165109
First seen Apr 06, 2026 · Last updated Jun 18, 2026 · Updated 12 times
Summary
This study enrolls adults with Down syndrome ages 25-55 into a ready-to-test group. Researchers will track memory, thinking, and brain changes over time to better understand how Alzheimer's disease develops in this population. The goal is to make future clinical trials faster and more effective by having a pre-screened group ready to join.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Advocate Medical Group Adult Down Syndrome Center
NOT_YET_RECRUITINGPark Ridge, Illinois, 60068, United States
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Barrow Neurological Institute
RECRUITINGPhoenix, Arizona, 85013, United States
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Case Western Reserve University
RECRUITINGBeachwood, Ohio, 44122, United States
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Cleveland Clinic, Lou Ruvo Center for Brain Health, Las Vegas
NOT_YET_RECRUITINGLas Vegas, Nevada, 89106, United States
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Indiana University
RECRUITINGIndianapolis, Indiana, 46202, United States
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Institut Jerome Lejeune
RECRUITINGParis, France, 75018, France
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Institute of Memory & Cognition, Tallaght University Hospital
RECRUITINGDublin, Ireland, 24, Ireland
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Linda Crnic Institute for Down Syndrome, University of Colorado
RECRUITINGAurora, Colorado, 80045, United States
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Massachusetts General Hospital, Co-Enrolling through ABC-DS Only
RECRUITINGBoston, Massachusetts, 02114, United States
Contact
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New York State Institute for Basic Research in Developmental Disabilities (SIBRDD), Co-Enrolling through ABC-DS Only
RECRUITINGStaten Island, New York, 10314, United States
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Oregon Health & Science University
NOT_YET_RECRUITINGPortland, Oregon, 97239, United States
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Sant Pau Biomedical Research Institute (IIB Sant Pau)
RECRUITINGBarcelona, 08041, Spain
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University of California, Irvine School of Medicine, Co-Enrolling through ABC-DS Only
RECRUITINGOrange, California, 92868, United States
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University of Cambridge, Co-Enrolling through ABC-DS Only
RECRUITINGCambridge, CB2 1TN, United Kingdom
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University of Cincinnati
NOT_YET_RECRUITINGCincinnati, Ohio, 45219, United States
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University of Kansas Medical Center
RECRUITINGKansas City, Kansas, 66160, United States
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University of Kentucky, Co-Enrolling through ABC-DS Only
RECRUITINGLexington, Kentucky, 40504, United States
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University of Pittsburgh, Co-Enrolling through ABC-DS Only
RECRUITINGPittsburgh, Pennsylvania, 15213, United States
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University of Texas Health San Antonio, Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases
RECRUITINGSan Antonio, Texas, 78229, United States
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University of Wisconsin - Madison, Waisman Center, Co-Enrolling through ABC-DS Only
RECRUITINGMadison, Wisconsin, 53705, United States
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Vanderbilt University Medical Center Center for Cognitive Medicine
RECRUITINGNashville, Tennessee, 37212, United States
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Washington University, St. Louis
RECRUITINGSt Louis, Missouri, 63108, United States
Contact
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.