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Double nerve block may cut opioid use after lung surgery

NCT ID NCT03852862

Symptom relief Sponsor: University Hospital, Rouen Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether using two different nerve blocks together, instead of just one, can reduce the amount of strong painkillers (opioids) needed after lung surgery. 112 adults scheduled for video-assisted thoracoscopic surgery received either a single block or a double block with the anesthetic ropivacaine. The main goal was to see if the double block lowered opioid use.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ropivacaine
What this could lead to
If successful, this approach could reduce the need for strong painkillers after lung surgery, leading to faster recovery and fewer side effects.
What could go wrong
This is a small, single-center study. The benefit of adding a second block may be small or not apply to all patients. There are also rare risks like bleeding or nerve injury from the injections.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

112 people

The number who actually took part.

Started

May 2019

Finished

Nov 2020

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patient aged 18 to 75 years; * Programmed for unilateral videothoracoscopy for anatomical resection (segmentectomy, lobectomy); * Subject affiliated to a social security scheme; * Subject having signed an informed consent Exclusion Criteria: * Chronic treatment with opiates; * Contraindication to administration of morphine; * Allergy to local anesthetics or contraindications to the use of ropivacaine; * Contraindication to the realization of paravertebral blocks and serratus; * Pregnancy, breastfeeding; * Severe obesity (BMI \> 40 kg/m²); * Renal impairment (GFR \< 30 mL/min) or known severe hepatic impairment; * Difficulties of comprehension preventing the collection of consent and the realization of the study;

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anesthesia Video assisted thoracoscopy

Contacts and locations

Locations

  • Rouen University Hospital

    Rouen, France

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