Brain wave test may finally distinguish real tics from functional ones

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

* INCLUSION CRITERIA: In order to be eligible to participate in this study, an individual must meet all of the following criteria: * Capacity to provide informed consent (self-consent) * Stated willingness to comply with all study procedures and availability for the duration of the study * Male or female, aged 18-80 * Agreement to adhere to Lifestyle Considerations prior to and during the physiological testing visit. Inclusion criteria for patients with functional tics or tics \- Diagnosed with functional motor tics or motor tics Inclusion criteria for healthy controls \- Have no neurological or psychiatric disorders established by history and physical/neurological examination EXCLUSION CRITERIA: * Self-reported consumption of \>14 alcoholic drinks/week\* for a man and \>7 alcoholic drinks/week for a woman * Use of prescription drugs and other illicit drugs that may suppress tics such as dopamine blocking agents and antipsychotics during a certain time period prior to the neurophysiological testing session.\*\* * Clinically significant abnormal movements on neurological examination except for tics. * Contraindications to EEG or EMG procedures, including skin lesions at electrode sites or hypersensitivity to electrode materials. * History of or current brain tumor, stroke, head trauma with loss of consciousness. * Epilepsy or seizures in the past 12 months. * Have a Baclofen pump, or have neurostimulators for pain. * Pregnant women * Self-reported current major depression or Beck Depression Inventory II (BDI-II) score \>19, Generalized Anxiety Disorder 7-item scale (GAD-7) score \> 9, or any major current psychiatric illness. * Presence of any metal in the eye or skull area such as a brain stimulator, shrapnel, surgical metal, clips in the brain, cochlear implants, metal fragments in the eye. * Presence of pacemaker, intracardiac lines, implanted pumps or stimulators. * Unable to comply with the requirements of the study procedures. * Vocal tics only tested with Modified Rush Video-Based Tic Rating Scale. * Low Premonitory Urge for Tics Scale (PUTS) score \< 9 (maximum 36) with low willingness for tics (patient groups only, not applicable in healthy volunteers). * Note: 1 standard alcoholic drink is 0.6 ounce (14 grams) of pure alcohol. * Note: The certain time period depends on different drugs used. Five half-lives will be selected. The drug is considered effectively eliminated from the body after this time period because the concentration of the drug reaches around 3% of the orininal concentration.