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Can a simple dental procedure save teeth from root canals?

NCT ID NCT06495242

Disease control Sponsor: King Abdullah University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time

Summary

This trial compares two dental procedures—direct pulp capping and partial pulpotomy—for treating permanent teeth with deep cavities that expose the pulp. Adults with deep caries and reversible pulpitis will be randomly assigned to one of the two procedures. The study will follow participants for up to five years to see which procedure better resolves symptoms and maintains pulp vitality, potentially helping dentists choose the best approach to save natural teeth.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Two dental procedures: direct pulp capping and partial pulpotomy
What this could lead to
If successful, this could help dentists choose the best procedure to save teeth with deep cavities, avoiding root canals or tooth loss.
What could go wrong
This is a single-center trial with 120 patients, and results may not apply to all cases. There is a risk of pulp inflammation or failure, leading to further treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 120 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2023

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

12 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Non -contributory medical history (ASA 1) * Molar tooth with extremely deep caries extending\>2/3 of dentin or exposing the pulp on the periapical radiograph * The tooth should give positive response to cold testing * Clinical diagnosis of reversible pulpitis with mild to moderate symptoms * The tooth is restorable, probing pocket depth and mobility are within normal limits * No signs of pulpal necrosis including sinus tract or swelling * No radiographic evidence of periapical changes indicative of apical periodontitis Exclusion Criteria: Immature teeth * Nonvital teeth * Irreversible pulpitis and periapical periodontitis, i.e spontaneous and lingering pain. * Inability to achieve hemostasis after 6 minutes of application of 5% NaOCl moist pellet * No pulp exposure after nonselective caries removal

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Conditions

The condition(s) this trial relates to.

dentin caries Pain pulpitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Deep caries

Contacts and locations

Locations

  • Faculty of Dentistry, Jordan University of Science and Technology

    Irbid, Irbid Governorate, 3030, Jordan

More trials for these conditions

Other studies related to the condition(s) this trial covers.