Can a new cement save teeth with deep decay better than the standard?
NCT ID NCT06256601
First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time
Summary
This trial tests whether a calcium silicate cement outperforms the standard calcium hydroxide material when used to treat deep cavities close to the tooth's nerve. Adults aged 18 to 45 with at least one deep cavity will receive one of the two materials after partial decay removal. Researchers will check the restorations for fractures, sensitivity, and signs of further decay over 18 months.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- calcium silicate cement (Theracal) compared to calcium hydroxide (Dycal)
- What this could lead to
- If calcium silicate proves more effective, it could become a preferred material for preserving tooth vitality in deep cavities.
- What could go wrong
- This is a small, early-stage trial with 80 participants, so results may not apply broadly. Both materials are already in use, so major breakthroughs are unlikely.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
80 people
The number who actually took part.
- Started
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Jul 2023
- Finished
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Jul 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 45 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * The age of the patient should be ranged between 18-45. * The score of the caries lesion should be D3. * Absence of a history of spontaneous pain in the teeth to be included. * Absence of periapical pathology * No displacement or mobility of the teeth. * Caries should not have reached the pulp tissue, and there should be no root fractures. * Restorable by direct restoration and functional Exclusion Criteria: * Poor oral hygiene of the participant. * Parafunctional habits such as teeth clenching or grinding. * Caries extending to the underneath of gingival margin * Severe periodontal pathology * Previous restored teeth * Teeth undergoing orthodontic treatment
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hacettepe University
Ankara, 06100, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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