Olive oil and prebiotics: a tasty way to fight muscle loss in seniors?
NCT ID NCT05485402
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether a diet rich in a special olive oil (high in phenolic compounds) plus prebiotic supplements could help people aged 60-80 who have sarcopenia (age-related muscle loss). The goal was to see if this approach could improve muscle mass, strength, and walking speed, and also reduce heart disease risk. 39 participants followed the diet for 12 weeks, with a 12-week follow-up to see if any benefits lasted.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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39 people
The number who actually took part.
- Started
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Sep 2022
- Finished
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May 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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60 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Men and women with and age equal to or greater than 60 years and until 80 years. * Written informed consent provided before the initial visit. * Sarcopenia assessment: low muscle strength based on grip dynamometry, kg (men \<30 kg; women \<20 kg) or low skeletal muscle mass index (SMI) based on bioimpedance analysis (BIA), kg/m2 (men \<8,87 kg/m2; women \<6,42 kg/m2) or low physical performance or physical function based on 4m gait speed, m/s (≤0,8 m/s) Exclusion Criteria: * Type 2 or insulin-dependent diabetes diagnosed. * Anemia (hemoglobin ≤13 g/dL in men and ≤12 g/dL in women). * Intestinal malabsorption diseases. * Fructose and/or sucrose intolerance. * Malnutrition (assessed by albumin \<3,5 g/dl). * Renal diseases. * Chronic alcoholism. * Current or past participation in a clinical trial or consumption of a research product in the 30 days prior to inclusion in the study. * Institutionalized elderly. * Failure to follow the study guidelines.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Universitat Rovira i Virgili
Reus, Tarragona, 43201, Spain
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