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Baking soda and veggies tested as cheap kidney protectors
NCT ID NCT06046924
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether reducing dietary acid with fruits and vegetables or sodium bicarbonate (baking soda) can slow chronic kidney disease in people with high blood pressure. 153 participants were followed for 5 years to measure kidney function and heart risk markers. The goal is to find a simple, affordable way to protect kidneys.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- fruits and vegetables or sodium bicarbonate (baking soda)
- What this could lead to
- If it works, this could point toward a simple, low-cost way to slow chronic kidney disease and reduce heart risks using diet or baking soda.
- What could go wrong
- This is a small, completed study with 153 participants. Results may not apply to everyone, and dietary changes can be hard to maintain long-term.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
153 people
The number who actually took part.
- Started
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Jun 1996
- Finished
-
Dec 2011
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 70 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Non-malignant high blood pressure or hypertension * 18-70 years old * Urine albumin-to-creatine ratio \> 200 mg/g creatinine * Estimated glomerular filtration rate (eGFR) greater than or equal to 90 ml/min/1.73 m2 * Serum total CO2 (TCO2) \> 22 mmol/l * Greater than or equal to 2 primary care visits in the preceding year * Able to provide informed consent Exclusion Criteria: * Malignant hypertension or history thereof * Primary kidney disease or findings consistent thereof such as \> 3 red blood cells per high powered field of urine or urine cellular casts * History of diabetes or fasting glucose greater than or equal to 110 mg/dl * History of hematologic disorders, malignancies, chronic infections, current pregnancy, history or clinical evidence of cardiovascular disease * Peripheral edema or diagnosis associated with edema such as heart/liver failure or nephrotic syndrome * Unable to provide consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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