Which diet works best? new study pits mediterranean, Low-Carb, and High-Protein against each other
NCT ID NCT07314177
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested three different diets—a traditional Mediterranean diet, a low-carb Mediterranean diet, and a high-protein diet—in 45 adults who are overweight or have obesity. Over 12 weeks, researchers measured changes in weight, body fat, muscle, and blood markers like cholesterol and blood sugar. The goal was to see which diet best improves body composition and metabolic health, helping guide future dietary advice.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
45 people
The number who actually took part.
- Started
-
Sep 2024
- Finished
-
Jun 2025
- Lead sponsor
-
A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
20 to 70 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 20-70 years * Body mass index (BMI) ≥ 25 kg/m² (overweight or obesity) * Stable body weight (± 2 kg) in the last 3 months prior to screening * Willingness to follow one of the prescribed dietary interventions for 12 weeks * Ability to attend scheduled follow-up visits and complete study assessments * Provided written informed consent prior to study participation Exclusion Criteria: * Diagnosis of type 1 diabetes, cardiovascular disease, cancer, chronic kidney disease, liver disease, or other serious chronic conditions that could interfere with the intervention * Pregnancy or breastfeeding * Current participation in another clinical trial * History of bariatric surgery or weight-loss program within the past 6 months * Use of medications known to affect body weight, metabolism, or appetite (e.g., glucocorticoids, weight-loss drugs, antipsychotics) * Any food allergy or intolerance that would preclude adherence to the assigned diet * Alcohol or substance abuse * Any condition or circumstance that, in the opinion of the investigators, would make the participant unsuitable for the study
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Cardiometabolic risk factors are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Edificio SAI
Zaragoza, Spain
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a sugary drink before Weight-Loss surgery speed up gut recovery?
- Do obese children with autism face different heart risks?
- Digital twin of the human body may forecast health decline before it happens
- A cheap blood test could flag hidden liver fat in metabolic syndrome
- Emergency room visit could be a turning point for metabolic health
- Coffee grounds probiotic could reshape gut health and fight inflammation