OBESITY & OVERWEIGHT

This study tests whether giving overweight teens free fruits and vegetables from a local farm, along with educational videos, can help them eat better and improve their blood pressure and weight. About 50 teens aged 12-17 will take part for 8 weeks. Researchers will track how man…

This study tests a new drug called RN3161, given alone or with another weight loss drug (tirzepatide), in adults with overweight or obesity. The goal is to check safety and how the body handles the drug. About 104 people will take part, and the study is currently recruiting.

This study looks at whether adding a GLP-1 appetite suppressant to behavioral therapy helps people with severe obesity and binge eating disorder more than therapy alone. About 80 adults will be split into two groups: one gets the drug plus therapy, the other gets therapy only. Re…

This study tests an injection called UBT251 in 180 adults who are overweight or obese and have chronic kidney disease. The goal is to see if it can reduce protein in the urine, a sign of kidney damage, over 24 weeks. Participants will receive either the drug or a placebo, and the…

This study looks at whether eating grape powder can help the gut and immune system in adults with obesity. Researchers will measure gut bacteria, inflammation, and stress levels. The goal is to see if grapes can improve health in this group.

This study tests whether an upgraded smartphone app helps people follow their bariatric surgery plan better than the standard app. About 200 adults having weight-loss surgery will use either the regular or an enhanced version of the "Get Ready" app. Researchers will track weight …

This study tests a mobile app called FoodTraining that trains people to better control their impulses around food. About 113 adults with obesity, binge-eating disorder, or bulimia will use the app for 4 weeks alongside their usual treatment. Researchers will measure changes in em…

This study tests whether limiting eating to specific hours of the day (early or late) helps control blood sugar and improve heart health in people who are overweight and have normal blood sugar, prediabetes, or type 2 diabetes. Researchers will monitor 30 participants' glucose le…

This study compares two methods (pressure support ventilation and T-piece) used to test if overweight ICU patients are ready to have their breathing tube removed. About 100 adults with a BMI of 25 or higher who have been on a ventilator for over 24 hours will be randomly assigned…

This study looks at how blocking the ghrelin receptor (a hunger signal) affects appetite and metabolism in people with obesity who are already taking semaglutide. About 24 adults will receive either a natural blocker called LEAP2 or a placebo during two visits. The goal is to und…

This study looks at how taking multiple medications affects the health of elderly people with chronic diseases like heart disease, diabetes, and high blood pressure. Researchers will survey 2000 patients aged 65 and older in Shaanxi Province, China, over two years. The goal is to…