OBESITY & OVERWEIGHT

This study is testing whether a more interactive version of a smartphone app helps people follow their care plan better after weight-loss (bariatric) surgery. Researchers will compare the new app version to the standard one in 200 patients. They will measure how well patients sti…

This study compares two different breathing test methods to determine which one better prepares overweight and obese ICU patients to have their breathing tubes safely removed. Researchers will test 100 adult patients who have been on ventilators for over 24 hours, randomly assign…

This study is looking at whether adding GLP-1 weight-loss drugs to a therapy program works better than therapy alone for people with severe obesity and binge eating disorder. It will follow 80 adults for a year, tracking their weight, eating disorder symptoms, and whether they de…

This study is testing a new drug called RN3161 to see if it is safe and helps with weight loss. It will be given alone and in combination with an existing weight loss medication, tirzepatide, to adults who are overweight or have obesity. The main goals are to check for side effec…

This study is testing a mobile app called FoodTraining, which is designed to help people with obesity, binge-eating disorder, or bulimia nervosa strengthen their self-control around food. Over 4 weeks, participants will use the app alongside their standard treatment. Researchers …

This study is testing if restricting meals to an 8-hour window, either early or late in the day, can improve blood sugar control and heart health in people who are overweight and have prediabetes or type 2 diabetes. It will involve 30 participants who will try both eating schedul…

This study is testing whether an experimental injection called UBT251 can help protect kidney function and reduce body weight in adults who are overweight or obese and have chronic kidney disease. About 180 participants will receive either the UBT251 injection or a placebo (dummy…

This study is testing whether giving overweight teens free fruits and vegetables from a local farm for 8 weeks, along with educational videos, helps them eat healthier and improves their blood pressure and weight. Researchers will track 50 teens to see if they pick up their weekl…

This study aims to understand how the body's hunger signals work when a person is already taking a medication like semaglutide for weight loss. Researchers will give 24 participants with obesity an infusion that temporarily blocks a key hunger hormone (ghrelin) or a placebo, whil…

This study is testing whether adding chia or hemp seeds to lunch foods helps people feel fuller and more satisfied after eating. Researchers will serve seed-enhanced meals to 24 adults with overweight or obesity and measure how much they eat and how hungry they feel afterward. Th…

This study aims to understand how taking many different medications affects the health of older adults living with chronic diseases like heart disease, diabetes, and high blood pressure. Researchers will follow 2,000 participants aged 65 and older for two years, asking them to co…

This study is looking to see if eating freeze-dried grape powder for 4 weeks can improve gut bacteria, reduce body-wide inflammation, and lower stress in adults with obesity. 50 participants will try both the grape powder and a placebo powder in a random order to compare the effe…